Crabescein, CAS number 102072-98-0

Product Name: Crabescein
CAS Number: 102072-98-0
Developed By: Find Suppliers
Molecular Formula: C₂₅H₂₂N₂O₅S₂
Molecular Weight: 494.6 g/mol
Chemical Structure: 4-(3-hydroxy-6-oxoxanthen-9-yl)-1-N,3-N-bis(2-sulfanyl ethyl)benzene-1,3-dicarboxamide
Synonyms: Fluorescein derivative
Role: Used in biochemical research, particularly for studying protein dynamics
Primary Application: Understanding immunoglobulin (IgG) behavior and interaction, particularly the hinge region disulfide bond.
Mechanism: Crabescein covalently binds to the third disulfide bond in the IgG hinge region, helping measure the rotational correlation time for protein dynamics.
Properties: Offers advantages in protein labeling and tracking, especially for IgG proteins.
Production Process: The synthesis involves modifying the core fluorescein structure to introduce a unique 1,3-benzenedicarboxamide moiety, which enables dual-point attachments to proteins.
Purity and Testing: The production process ensures high purity and consistency, with rigorous testing to confirm the compound's effectiveness for advanced biochemical applications.